Entrez Gene ID | 10257 |
---|---|
Official Gene Symbol | ABCC4 (GeneCards) |
Full name | ATP binding cassette subfamily C member 4 |
Location | 13q32.1 |
Other ids | Vega : OTTHUMG00000017216 MIM : 605250 HGNC : HGNC:55 Ensembl : ENSG00000125257 |
Other names | MRP4, MOATB, MOAT-B |
Summary | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
Found 4 variants in this database.
Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
---|---|---|---|---|---|---|---|
1122 | 10257 | ABCC4 | 13 | 95859031 | 95859031 | Human Skin Fibroblasts | HiSeq 2500 |
17373 | 10257 | ABCC4 | 13 | 95848406 | 95848406 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
17655 | 10257 | ABCC4 | 13 | 96020285 | 96020285 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
17673 | 10257 | ABCC4 | 13 | 95845417 | 95845417 | Asymptomatic | HiSeq 2500 HiSeq X Ten |