| Entrez Gene ID | 10714 |
|---|---|
| Official Gene Symbol | POLD3 (GeneCards) |
| Full name | DNA polymerase delta 3, accessory subunit |
| Location | 11q13.4 |
| Other ids | Vega : OTTHUMG00000165621 MIM : 611415 HGNC : HGNC:20932 Ensembl : ENSG00000077514 |
| Other names | P66, P68, PPP1R128 |
| Summary | This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012] |
Found 1 variant in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 15823 | 10714 | POLD3 | 11 | 74381158 | 74381158 | Cockayne syndrome | HiSeq X Ten |