| Entrez Gene ID | 10846 |
|---|---|
| Official Gene Symbol | PDE10A (GeneCards) |
| Full name | phosphodiesterase 10A |
| Location | 6q27 |
| Other ids | Vega : OTTHUMG00000015986 MIM : 610652 HGNC : HGNC:8772 Ensembl : ENSG00000112541 |
| Other names | ADSD2, IOLOD, HSPDE10A, PDE10A19, LINC00473 |
| Summary | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011] |
Found 8 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 8914 | 10846 | PDE10A | 6 | 166056666 | 166056666 | Asymptomatic | HiSeq X Ten |
| 8991 | 10846 | PDE10A | 6 | 165875963 | 165875963 | Asymptomatic | HiSeq X Ten |
| 9016 | 10846 | PDE10A | 6 | 166304417 | 166304417 | Asymptomatic | HiSeq X Ten HiSeq 2000 |
| 9542 | 10846 | PDE10A | 6 | 166296502 | 166296502 | Asymptomatic | HiSeq X Ten HiSeq 2000 |
| 9729 | 10846 | PDE10A | 6 | 166092231 | 166092231 | Asymptomatic | HiSeq X Ten HiSeq 2000 |
| 10036 | 10846 | PDE10A | 6 | 165973880 | 165973880 | Asymptomatic | HiSeq X Ten HiSeq 2000 |
| 10277 | 10846 | PDE10A | 6 | 166063471 | 166063471 | Xeroderma Pigmentosum | HiSeq X Ten HiSeq 2000 |
| 23138 | 10846 | PDE10A | 6 | 166169007 | 166169007 | Asymptomatic | HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning |