Entrez Gene ID	11122
Official Gene Symbol	PTPRT (GeneCards)
Full name	protein tyrosine phosphatase, receptor type T
Location	20q12-q13.11
Other ids	Vega : OTTHUMG00000033040 MIM : 608712 HGNC : HGNC:9682 Ensembl : ENSG00000196090
Other names	RPTPrho
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

Variants

Found 53 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
21160	11122	PTPRT	20	40807335	40807335	Asymptomatic	HiSeq X Ten
21303	11122	PTPRT	20	41970181	41970181	Asymptomatic	HiSeq X Ten
21316	11122	PTPRT	20	41049719	41049719	Asymptomatic	HiSeq X Ten
21326	11122	PTPRT	20	40848779	40848779	Asymptomatic	HiSeq X Ten
21465	11122	PTPRT	20	40753710	40753710	Cockayne syndrome	HiSeq X Ten
21471	11122	PTPRT	20	40725741	40725741	Cockayne syndrome	HiSeq X Ten
21521	11122	PTPRT	20	40827929	40827929	Xeroderma Pigmentosum	HiSeq X Ten
21529	11122	PTPRT	20	41796730	41796730	Xeroderma Pigmentosum	HiSeq X Ten
28577	11122	PTPRT	20	41734457	41734457	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning
28612	11122	PTPRT	20	41449215	41449215	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning
31128	11122	PTPRT	20	41306563	41306563	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31129	11122	PTPRT	20	41306563	41306563	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31130	11122	PTPRT	20	40877354	40877354	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31131	11122	PTPRT	20	40877354	40877354	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31132	11122	PTPRT	20	40980806	40980806	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31133	11122	PTPRT	20	41101036	41101036	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31134	11122	PTPRT	20	40743942	40743942	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31135	11122	PTPRT	20	41408877	41408877	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31136	11122	PTPRT	20	40733211	40733211	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
31137	11122	PTPRT	20	41400090	41400090	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32578	11122	PTPRT	20	40827937	40827937	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32579	11122	PTPRT	20	40944393	40944393	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32580	11122	PTPRT	20	41306745	41306745	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32581	11122	PTPRT	20	41419898	41419898	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32582	11122	PTPRT	20	41419925	41419925	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32583	11122	PTPRT	20	41419900	41419900	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32584	11122	PTPRT	20	41100995	41100995	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32585	11122	PTPRT	20	40827924	40827924	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32586	11122	PTPRT	20	41101024	41101024	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32587	11122	PTPRT	20	40790000	40790000	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32588	11122	PTPRT	20	40714410	40714410	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32589	11122	PTPRT	20	40709566	40709566	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32590	11122	PTPRT	20	41400186	41400186	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32591	11122	PTPRT	20	41400164	41400164	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32592	11122	PTPRT	20	41100906	41100906	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32593	11122	PTPRT	20	40733276	40733276	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32594	11122	PTPRT	20	41400176	41400176	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32595	11122	PTPRT	20	41101044	41101044	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32596	11122	PTPRT	20	41306711	41306711	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32597	11122	PTPRT	20	40710600	40710600	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32598	11122	PTPRT	20	41076938	41076938	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
32599	11122	PTPRT	20	40944425	40944425	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33761	11122	PTPRT	20	40790142	40790142	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33762	11122	PTPRT	20	41419917	41419917	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33763	11122	PTPRT	20	41306553	41306553	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33764	11122	PTPRT	20	40979350	40979350	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33765	11122	PTPRT	20	40709551	40709551	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33766	11122	PTPRT	20	41420093	41420093	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33767	11122	PTPRT	20	41419943	41419943	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33768	11122	PTPRT	20	40713347	40713347	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
33769	11122	PTPRT	20	40730786	40730786	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
34169	11122	PTPRT	20	40980879	40980879	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel
34170	11122	PTPRT	20	41420059	41420059	Asymptomatic	HiSeq X Ten Single cell Sequencing Cell cloning NGS gene panel

PTPRT (Entrez ID: 11122)

Variants