| Entrez Gene ID |
1147 |
| Official Gene Symbol |
CHUK (GeneCards) |
| Full name |
conserved helix-loop-helix ubiquitous kinase |
| Location |
10q24.31 |
| Other ids |
Vega : OTTHUMG00000018899
MIM : 600664
HGNC : HGNC:1974
Ensembl : ENSG00000213341
|
| Other names |
IKK1,
IKKA,
IKBKA,
TCF16,
NFKBIKA,
IKK-alpha
|
| Summary |
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008] |