DACH2 (Entrez ID: 117154)

Entrez Gene ID 117154
Official Gene Symbol DACH2 (GeneCards)
Full name dachshund family transcription factor 2
Location Xq21.2
Other ids Vega : OTTHUMG00000021944
MIM : 300608
HGNC : HGNC:16814
Ensembl : ENSG00000126733
Other names None
Summary This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Variants

Found 15 variants in this database.