| Entrez Gene ID | 1268 |
|---|---|
| Official Gene Symbol | CNR1 (GeneCards) |
| Full name | cannabinoid receptor 1 |
| Location | 6q15 |
| Other ids | Vega : OTTHUMG00000015184 MIM : 114610 HGNC : HGNC:2159 Ensembl : ENSG00000118432 |
| Other names | CB1, CNR, CB-R, CB1A, CB1R, CANN6, CB1K5 |
| Summary | This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] |
Found 6 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 9592 | 1268 | CNR1 | 6 | 89060742 | 89060742 | Asymptomatic | HiSeq X Ten |
| 9742 | 1268 | CNR1 | 6 | 88946909 | 88946909 | Asymptomatic | HiSeq X Ten |
| 10022 | 1268 | CNR1 | 6 | 88975571 | 88975571 | Asymptomatic | HiSeq X Ten |
| 10079 | 1268 | CNR1 | 6 | 89222177 | 89222177 | Cockayne syndrome | HiSeq X Ten |
| 10147 | 1268 | CNR1 | 6 | 89149779 | 89149779 | Cockayne syndrome | HiSeq X Ten |
| 26270 | 1268 | CNR1 | 6 | 89123936 | 89123936 | Asymptomatic | HiSeq X Ten Single cell Sequencing Cell cloning |