| Entrez Gene ID |
131450 |
| Official Gene Symbol |
CD200R1 (GeneCards) |
| Full name |
CD200 receptor 1 |
| Location |
3q13.2 |
| Other ids |
Vega : OTTHUMG00000159298
MIM : 607546
HGNC : HGNC:24235
Ensembl : ENSG00000163606
|
| Other names |
OX2R,
MOX2R,
CD200R,
HCRTR2
|
| Summary |
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |