ADRA2A (Entrez ID: 150)

Entrez Gene ID	150
Official Gene Symbol	ADRA2A (GeneCards)
Full name	adrenoceptor alpha 2A
Location	10q25.2
Other ids	Vega : OTTHUMG00000019050 MIM : 104210 HGNC : HGNC:281 Ensembl : ENSG00000150594
Other names	ADRA2, ADRAR, ZNF32, ADRA2R, ALPHA2AAR
Summary	Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]

Variants

Found 17 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
13847	150	ADRA2A	10	113821670	113821670	Asymptomatic	HiSeq X Ten
13955	150	ADRA2A	10	113633785	113633785	Asymptomatic	HiSeq X Ten HiSeq 2000
14007	150	ADRA2A	10	113501859	113501859	Asymptomatic	HiSeq X Ten HiSeq 2000
14353	150	ADRA2A	10	113452163	113452163	Asymptomatic	HiSeq X Ten HiSeq 2000
14420	150	ADRA2A	10	113643498	113643498	Asymptomatic	HiSeq X Ten HiSeq 2000
14421	150	ADRA2A	10	113672004	113672004	Asymptomatic	HiSeq X Ten HiSeq 2000
14520	150	ADRA2A	10	113227021	113227021	Asymptomatic	HiSeq X Ten HiSeq 2000
14606	150	ADRA2A	10	113325559	113325559	Asymptomatic	HiSeq X Ten HiSeq 2000
14662	150	ADRA2A	10	113399110	113399110	Asymptomatic	HiSeq X Ten HiSeq 2000
14701	150	ADRA2A	10	113133232	113133232	Asymptomatic	HiSeq X Ten HiSeq 2000
14706	150	ADRA2A	10	113246345	113246345	Cockayne syndrome	HiSeq X Ten HiSeq 2000
14707	150	ADRA2A	10	113315491	113315491	Cockayne syndrome	HiSeq X Ten HiSeq 2000
14807	150	ADRA2A	10	113673317	113673317	Cockayne syndrome	HiSeq X Ten HiSeq 2000
14865	150	ADRA2A	10	113622724	113622724	Xeroderma Pigmentosum	HiSeq X Ten HiSeq 2000
14944	150	ADRA2A	10	112970878	112970878	Xeroderma Pigmentosum	HiSeq X Ten HiSeq 2000
23503	150	ADRA2A	10	113613233	113613233	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
27113	150	ADRA2A	10	113130829	113130829	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning