| Entrez Gene ID | 154796 |
|---|---|
| Official Gene Symbol | AMOT (GeneCards) |
| Full name | angiomotin |
| Location | Xq23 |
| Other ids | Vega : OTTHUMG00000022216 MIM : 300410 HGNC : HGNC:17810 Ensembl : ENSG00000126016 |
| Other names | None |
| Summary | This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Found 2 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 28900 | 154796 | AMOT | X | 112121970 | 112121970 | Asymptomatic | Single cell Sequencing Cell cloning |
| 29258 | 154796 | AMOT | X | 112021879 | 112021879 | Autism Spectrum Disorders | Single cell Sequencing Cell cloning PASM |