Entrez Gene ID | 161725 |
---|---|
Official Gene Symbol | OTUD7A (GeneCards) |
Full name | OTU deubiquitinase 7A |
Location | 15q13.3 |
Other ids | Vega : OTTHUMG00000129275 MIM : 612024 HGNC : HGNC:20718 Ensembl : ENSG00000169918 |
Other names | OTUD7, C15orf16, C16ORF15, CEZANNE2 |
Summary | The protein encoded by this gene is a deubiquitinizing enzyme and possible tumor suppressor. The encoded protein acts on TNF receptor associated factor 6 (TRAF6) to control nuclear factor kappa B expression. However, this gene is downregulated by SNAIL1 in hepatocellular carcinoma cells, contributing to their progression and malignancy. [provided by RefSeq, Aug 2016] |
Found 4 variants in this database.
Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
---|---|---|---|---|---|---|---|
18887 | 161725 | OTUD7A | 15 | 31894914 | 31894914 | Asymptomatic | HiSeq X Ten |
18911 | 161725 | OTUD7A | 15 | 31928294 | 31928294 | Asymptomatic | HiSeq X Ten |
19157 | 161725 | OTUD7A | 15 | 31931279 | 31931279 | Asymptomatic | HiSeq X Ten |
19210 | 161725 | OTUD7A | 15 | 32317399 | 32317399 | Cockayne syndrome | HiSeq X Ten |