Entrez Gene ID	1788
Official Gene Symbol	DNMT3A (GeneCards)
Full name	DNA methyltransferase 3 alpha
Location	2p23.3
Other ids	Vega : OTTHUMG00000094777 MIM : 602769 HGNC : HGNC:2978 Ensembl : ENSG00000119772
Other names	TBRS, DNMT3A2, M.HsaIIIA
Summary	CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]

Variants

Found 139 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
1258	1788	DNMT3A	2	25468920	25468920	Aplastic Anaemia	HiSeq 2500
1259	1788	DNMT3A	2	25468920	25468920	Aplastic Anaemia	HiSeq 2500
3977	1788	DNMT3A	2	25587637	25587637	Asymptomatic	HiSeq 2500 HiSeq X Ten
22664	1788	DNMT3A	2	25459792	25459792	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning
30263	1788	DNMT3A	2	25470492	25470492	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30264	1788	DNMT3A	2	25463189	25463189	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30265	1788	DNMT3A	2	25458588	25458588	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30266	1788	DNMT3A	2	25458582	25458582	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30267	1788	DNMT3A	2	25457224	25457224	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30268	1788	DNMT3A	2	25463205	25463205	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30269	1788	DNMT3A	2	25463199	25463199	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30270	1788	DNMT3A	2	25457237	25457237	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30271	1788	DNMT3A	2	25463171	25463171	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30272	1788	DNMT3A	2	25457232	25457232	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30273	1788	DNMT3A	2	25463195	25463195	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30274	1788	DNMT3A	2	25457236	25457236	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30275	1788	DNMT3A	2	25458576	25458576	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30276	1788	DNMT3A	2	25458588	25458588	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30277	1788	DNMT3A	2	25458585	25458585	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30278	1788	DNMT3A	2	25458603	25458603	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30279	1788	DNMT3A	2	25457222	25457222	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30280	1788	DNMT3A	2	25463189	25463189	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30281	1788	DNMT3A	2	25458588	25458588	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30282	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30283	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30284	1788	DNMT3A	2	25458590	25458590	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30285	1788	DNMT3A	2	25457243	25457243	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30286	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30287	1788	DNMT3A	2	25458595	25458595	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30288	1788	DNMT3A	2	25463184	25463184	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30289	1788	DNMT3A	2	25463287	25463287	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30290	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30291	1788	DNMT3A	2	25457231	25457231	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30292	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30293	1788	DNMT3A	2	25463184	25463184	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30294	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30295	1788	DNMT3A	2	25457228	25457228	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30296	1788	DNMT3A	2	25463212	25463212	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30297	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30298	1788	DNMT3A	2	25463287	25463287	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30299	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30300	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30301	1788	DNMT3A	2	25463308	25463308	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30302	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30303	1788	DNMT3A	2	25457231	25457231	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30304	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30305	1788	DNMT3A	2	25463168	25463168	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30306	1788	DNMT3A	2	25463184	25463184	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30307	1788	DNMT3A	2	25458595	25458595	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30308	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30309	1788	DNMT3A	2	25463173	25463173	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30310	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30311	1788	DNMT3A	2	25463287	25463287	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30312	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30313	1788	DNMT3A	2	25463299	25463299	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30314	1788	DNMT3A	2	25458597	25458597	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30315	1788	DNMT3A	2	25463287	25463287	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30316	1788	DNMT3A	2	25463284	25463284	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30317	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30318	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30319	1788	DNMT3A	2	25463308	25463308	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30320	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30321	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30322	1788	DNMT3A	2	25463175	25463175	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30323	1788	DNMT3A	2	25470479	25470479	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30324	1788	DNMT3A	2	25458595	25458595	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30325	1788	DNMT3A	2	25463287	25463287	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30326	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30327	1788	DNMT3A	2	25470497	25470497	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30328	1788	DNMT3A	2	25463286	25463286	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30329	1788	DNMT3A	2	25458595	25458595	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30330	1788	DNMT3A	2	25458574	25458574	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30331	1788	DNMT3A	2	25457243	25457243	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30332	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30333	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30334	1788	DNMT3A	2	25457243	25457243	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30335	1788	DNMT3A	2	25463308	25463308	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30336	1788	DNMT3A	2	25463286	25463286	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30337	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30338	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30339	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30340	1788	DNMT3A	2	25463291	25463291	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30341	1788	DNMT3A	2	25458593	25458593	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30342	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30343	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30344	1788	DNMT3A	2	25463188	25463188	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30345	1788	DNMT3A	2	25458595	25458595	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30346	1788	DNMT3A	2	25457243	25457243	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30347	1788	DNMT3A	2	25457242	25457242	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30348	1788	DNMT3A	2	25470484	25470484	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30349	1788	DNMT3A	2	25463184	25463184	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30350	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30351	1788	DNMT3A	2	25463287	25463287	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30352	1788	DNMT3A	2	25463286	25463286	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30353	1788	DNMT3A	2	25463307	25463307	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30354	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30355	1788	DNMT3A	2	25470498	25470498	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30356	1788	DNMT3A	2	25463186	25463186	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30357	1788	DNMT3A	2	25463286	25463286	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30358	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30359	1788	DNMT3A	2	25470497	25470497	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30360	1788	DNMT3A	2	25463178	25463178	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30361	1788	DNMT3A	2	25470497	25470497	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30362	1788	DNMT3A	2	25463308	25463308	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30363	1788	DNMT3A	2	25470497	25470497	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30364	1788	DNMT3A	2	25470516	25470516	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30365	1788	DNMT3A	2	25463182	25463182	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30366	1788	DNMT3A	2	25457231	25457231	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30367	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30368	1788	DNMT3A	2	25457249	25457249	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30369	1788	DNMT3A	2	25463173	25463173	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30370	1788	DNMT3A	2	25463212	25463212	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30371	1788	DNMT3A	2	25458575	25458575	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30372	1788	DNMT3A	2	25463308	25463308	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30373	1788	DNMT3A	2	25463181	25463181	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30374	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30375	1788	DNMT3A	2	25463187	25463187	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30376	1788	DNMT3A	2	25463286	25463286	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30377	1788	DNMT3A	2	25457247	25457247	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30378	1788	DNMT3A	2	25463289	25463289	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30379	1788	DNMT3A	2	25458597	25458597	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30380	1788	DNMT3A	2	25463300	25463300	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30381	1788	DNMT3A	2	25458620	25458627	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30382	1788	DNMT3A	2	25463297	25463297	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30383	1788	DNMT3A	2	25463196	25463197	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30384	1788	DNMT3A	2	25458596	25458596	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30385	1788	DNMT3A	2	25458591	25458591	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30386	1788	DNMT3A	2	25463196	25463197	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30387	1788	DNMT3A	2	25463308	25463308	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30388	1788	DNMT3A	2	25463196	25463197	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30389	1788	DNMT3A	2	25463312	25463312	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30390	1788	DNMT3A	2	25463196	25463197	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30391	1788	DNMT3A	2	25463297	25463297	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30392	1788	DNMT3A	2	25458605	25458606	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30393	1788	DNMT3A	2	25463291	25463291	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30394	1788	DNMT3A	2	25458608	25458608	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30395	1788	DNMT3A	2	25463190	25463190	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30396	1788	DNMT3A	2	25463196	25463197	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP
30397	1788	DNMT3A	2	25458595	25458595	Asymptomatic	HiSeq 2500 HiSeq X Ten Single cell Sequencing Cell cloning smMIP

DNMT3A (Entrez ID: 1788)

Variants