EPHB1 (Entrez ID: 2047)

Entrez Gene ID 2047
Official Gene Symbol EPHB1 (GeneCards)
Full name EPH receptor B1
Location 3q22.2
Other ids Vega : OTTHUMG00000159804
MIM : 600600
HGNC : HGNC:3392
Ensembl : ENSG00000154928
Other names ELK, NET, Hek6, EPHT2
Summary Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]

Variants

Found 13 variants in this database.