| Entrez Gene ID | 2313 |
|---|---|
| Official Gene Symbol | FLI1 (GeneCards) |
| Full name | Fli-1 proto-oncogene, ETS transcription factor |
| Location | 11q24.3 |
| Other ids | Vega : OTTHUMG00000165792 MIM : 193067 HGNC : HGNC:3749 Ensembl : ENSG00000151702 |
| Other names | EWSR2, SIC-1, BDPLT21 |
| Summary | This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |