Entrez Gene ID | 23185 |
---|---|
Official Gene Symbol | LARP4B (GeneCards) |
Full name | La ribonucleoprotein domain family member 4B |
Location | 10p15.3 |
Other ids | Vega : OTTHUMG00000017534 MIM : 616513 HGNC : HGNC:28987 Ensembl : ENSG00000107929 |
Other names | LARP5, KIAA0217 |
Summary | This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012] |
Found 6 variants in this database.
Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
---|---|---|---|---|---|---|---|
1012 | 23185 | LARP4B | 10 | 876877 | 876877 | Human Skin Fibroblasts | HiSeq 2500 |
13996 | 23185 | LARP4B | 10 | 874771 | 874771 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
14146 | 23185 | LARP4B | 10 | 894767 | 894767 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
14213 | 23185 | LARP4B | 10 | 861483 | 861483 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
29121 | 23185 | LARP4B | 10 | 876865 | 876865 | Autism Spectrum Disorders | HiSeq 2500 HiSeq X Ten HiSeq Pyrosequencing |
29123 | 23185 | LARP4B | 10 | 876865 | 876865 | Autism Spectrum Disorders | HiSeq 2500 HiSeq X Ten HiSeq Pyrosequencing |