Entrez Gene ID	23236
Official Gene Symbol	PLCB1 (GeneCards)
Full name	phospholipase C beta 1
Location	20p12.3
Other ids	Vega : OTTHUMG00000031849 MIM : 607120 HGNC : HGNC:15917 Ensembl : ENSG00000182621
Other names	PLC-I, EIEE12, PI-PLC, PLC154, PLCB1A, PLCB1B, PLC-154, PLC-beta-1
Summary	The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Variants

Found 66 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
21108	23236	PLCB1	20	8816706	8816706	Asymptomatic	HiSeq X Ten
21112	23236	PLCB1	20	8289847	8289847	Asymptomatic	HiSeq X Ten
21153	23236	PLCB1	20	8323662	8323662	Asymptomatic	HiSeq X Ten
21180	23236	PLCB1	20	8240672	8240672	Asymptomatic	HiSeq X Ten
21233	23236	PLCB1	20	8652070	8652070	Asymptomatic	HiSeq X Ten
21284	23236	PLCB1	20	8730029	8730029	Asymptomatic	HiSeq X Ten
21335	23236	PLCB1	20	9021103	9021103	Asymptomatic	HiSeq X Ten
21421	23236	PLCB1	20	8838228	8838228	Asymptomatic	HiSeq X Ten
21427	23236	PLCB1	20	8131962	8131962	Asymptomatic	HiSeq X Ten
21478	23236	PLCB1	20	8233661	8233661	Cockayne syndrome	HiSeq X Ten
30998	23236	PLCB1	20	8131023	8131023	Asymptomatic	HiSeq X Ten NGS gene panel
30999	23236	PLCB1	20	8637915	8637915	Asymptomatic	HiSeq X Ten NGS gene panel
31000	23236	PLCB1	20	8689378	8689378	Asymptomatic	HiSeq X Ten NGS gene panel
31001	23236	PLCB1	20	8737809	8737809	Asymptomatic	HiSeq X Ten NGS gene panel
31002	23236	PLCB1	20	8745935	8745935	Asymptomatic	HiSeq X Ten NGS gene panel
31003	23236	PLCB1	20	8678363	8678363	Asymptomatic	HiSeq X Ten NGS gene panel
31004	23236	PLCB1	20	8717784	8717784	Asymptomatic	HiSeq X Ten NGS gene panel
31005	23236	PLCB1	20	8698463	8698463	Asymptomatic	HiSeq X Ten NGS gene panel
31006	23236	PLCB1	20	8722148	8722148	Asymptomatic	HiSeq X Ten NGS gene panel
32322	23236	PLCB1	20	8130977	8130977	Asymptomatic	HiSeq X Ten NGS gene panel
32323	23236	PLCB1	20	8717737	8717737	Asymptomatic	HiSeq X Ten NGS gene panel
32324	23236	PLCB1	20	8721036	8721036	Asymptomatic	HiSeq X Ten NGS gene panel
32325	23236	PLCB1	20	8637882	8637882	Asymptomatic	HiSeq X Ten NGS gene panel
32326	23236	PLCB1	20	8678336	8678336	Asymptomatic	HiSeq X Ten NGS gene panel
32327	23236	PLCB1	20	8709796	8709796	Asymptomatic	HiSeq X Ten NGS gene panel
32328	23236	PLCB1	20	8722178	8722178	Asymptomatic	HiSeq X Ten NGS gene panel
32329	23236	PLCB1	20	8862341	8862341	Asymptomatic	HiSeq X Ten NGS gene panel
32330	23236	PLCB1	20	8626814	8626814	Asymptomatic	HiSeq X Ten NGS gene panel
32331	23236	PLCB1	20	8717737	8717737	Asymptomatic	HiSeq X Ten NGS gene panel
32332	23236	PLCB1	20	8722174	8722174	Asymptomatic	HiSeq X Ten NGS gene panel
32333	23236	PLCB1	20	8745892	8745892	Asymptomatic	HiSeq X Ten NGS gene panel
32334	23236	PLCB1	20	8703062	8703063	Asymptomatic	HiSeq X Ten NGS gene panel
32335	23236	PLCB1	20	8678362	8678362	Asymptomatic	HiSeq X Ten NGS gene panel
32336	23236	PLCB1	20	8698392	8698392	Asymptomatic	HiSeq X Ten NGS gene panel
32337	23236	PLCB1	20	8770832	8770832	Asymptomatic	HiSeq X Ten NGS gene panel
32338	23236	PLCB1	20	8713994	8713994	Asymptomatic	HiSeq X Ten NGS gene panel
32339	23236	PLCB1	20	8609072	8609072	Asymptomatic	HiSeq X Ten NGS gene panel
32340	23236	PLCB1	20	8130965	8130965	Asymptomatic	HiSeq X Ten NGS gene panel
32341	23236	PLCB1	20	8639283	8639283	Asymptomatic	HiSeq X Ten NGS gene panel
32342	23236	PLCB1	20	8862278	8862278	Asymptomatic	HiSeq X Ten NGS gene panel
32343	23236	PLCB1	20	8698325	8698325	Asymptomatic	HiSeq X Ten NGS gene panel
32344	23236	PLCB1	20	8637829	8637829	Asymptomatic	HiSeq X Ten NGS gene panel
32345	23236	PLCB1	20	8665592	8665592	Asymptomatic	HiSeq X Ten NGS gene panel
32346	23236	PLCB1	20	8770179	8770179	Asymptomatic	HiSeq X Ten NGS gene panel
32347	23236	PLCB1	20	8717804	8717804	Asymptomatic	HiSeq X Ten NGS gene panel
32348	23236	PLCB1	20	8637906	8637906	Asymptomatic	HiSeq X Ten NGS gene panel
33593	23236	PLCB1	20	8862441	8862442	Asymptomatic	HiSeq X Ten NGS gene panel
33594	23236	PLCB1	20	8717833	8717833	Asymptomatic	HiSeq X Ten NGS gene panel
33595	23236	PLCB1	20	8862337	8862337	Asymptomatic	HiSeq X Ten NGS gene panel
33596	23236	PLCB1	20	8862337	8862337	Asymptomatic	HiSeq X Ten NGS gene panel
33597	23236	PLCB1	20	8862337	8862337	Asymptomatic	HiSeq X Ten NGS gene panel
33598	23236	PLCB1	20	8352092	8352092	Asymptomatic	HiSeq X Ten NGS gene panel
33599	23236	PLCB1	20	8628584	8628584	Asymptomatic	HiSeq X Ten NGS gene panel
33600	23236	PLCB1	20	8352092	8352092	Asymptomatic	HiSeq X Ten NGS gene panel
33601	23236	PLCB1	20	8628584	8628584	Asymptomatic	HiSeq X Ten NGS gene panel
33602	23236	PLCB1	20	8717839	8717839	Asymptomatic	HiSeq X Ten NGS gene panel
33603	23236	PLCB1	20	8755266	8755266	Asymptomatic	HiSeq X Ten NGS gene panel
33604	23236	PLCB1	20	8665593	8665593	Asymptomatic	HiSeq X Ten NGS gene panel
33605	23236	PLCB1	20	8755266	8755266	Asymptomatic	HiSeq X Ten NGS gene panel
33606	23236	PLCB1	20	8639337	8639337	Asymptomatic	HiSeq X Ten NGS gene panel
33607	23236	PLCB1	20	8709728	8709728	Asymptomatic	HiSeq X Ten NGS gene panel
33608	23236	PLCB1	20	8862338	8862338	Asymptomatic	HiSeq X Ten NGS gene panel
33609	23236	PLCB1	20	8698413	8698413	Asymptomatic	HiSeq X Ten NGS gene panel
33610	23236	PLCB1	20	8862441	8862441	Asymptomatic	HiSeq X Ten NGS gene panel
34138	23236	PLCB1	20	8665730	8665730	Asymptomatic	HiSeq X Ten NGS gene panel
34139	23236	PLCB1	20	8717804	8717804	Asymptomatic	HiSeq X Ten NGS gene panel

PLCB1 (Entrez ID: 23236)

Variants