| Entrez Gene ID |
23334 |
| Official Gene Symbol |
SZT2 (GeneCards) |
| Full name |
SZT2, KICSTOR complex subunit |
| Location |
1p34.2 |
| Other ids |
Vega : OTTHUMG00000007423
MIM : 615463
HGNC : HGNC:29040
Ensembl : ENSG00000198198
|
| Other names |
SZT2A,
SZT2B,
EIEE18,
C1orf84,
KIAA0467
|
| Summary |
The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011] |