| Entrez Gene ID | 2587 |
|---|---|
| Official Gene Symbol | GALR1 (GeneCards) |
| Full name | galanin receptor 1 |
| Location | 18q23 |
| Other ids | Vega : OTTHUMG00000132875 MIM : 600377 HGNC : HGNC:4132 Ensembl : ENSG00000166573 |
| Other names | GALNR, GALNR1 |
| Summary | The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008] |
Found 10 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 20291 | 2587 | GALR1 | 18 | 75187588 | 75187588 | Asymptomatic | HiSeq X Ten |
| 20422 | 2587 | GALR1 | 18 | 75458121 | 75458121 | Asymptomatic | HiSeq X Ten |
| 20430 | 2587 | GALR1 | 18 | 75065985 | 75065985 | Asymptomatic | HiSeq X Ten |
| 20454 | 2587 | GALR1 | 18 | 75531186 | 75531186 | Asymptomatic | HiSeq X Ten |
| 20562 | 2587 | GALR1 | 18 | 75251988 | 75251988 | Asymptomatic | HiSeq X Ten |
| 20563 | 2587 | GALR1 | 18 | 75262601 | 75262601 | Asymptomatic | HiSeq X Ten |
| 20603 | 2587 | GALR1 | 18 | 75270889 | 75270889 | Asymptomatic | HiSeq X Ten |
| 20712 | 2587 | GALR1 | 18 | 75476473 | 75476473 | Cockayne syndrome | HiSeq X Ten |
| 20722 | 2587 | GALR1 | 18 | 75234824 | 75234824 | Cockayne syndrome | HiSeq X Ten |
| 20775 | 2587 | GALR1 | 18 | 75425137 | 75425137 | Xeroderma Pigmentosum | HiSeq X Ten |