| Entrez Gene ID |
26512 |
| Official Gene Symbol |
INTS6 (GeneCards) |
| Full name |
integrator complex subunit 6 |
| Location |
13q14.3 |
| Other ids |
Vega : OTTHUMG00000016945
MIM : 604331
HGNC : HGNC:14879
Ensembl : ENSG00000102786
|
| Other names |
HDB,
INT6,
DBI-1,
DDX26,
DICE1,
DDX26A,
Notchl2
|
| Summary |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015] |