| Entrez Gene ID | 2735 |
|---|---|
| Official Gene Symbol | GLI1 (GeneCards) |
| Full name | GLI family zinc finger 1 |
| Location | 12q13.3 |
| Other ids | Vega : OTTHUMG00000167332 MIM : 165220 HGNC : HGNC:4317 Ensembl : ENSG00000111087 |
| Other names | GLI |
| Summary | This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
Found 1 variant in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 29249 | 2735 | GLI1 | 12 | 57865430 | 57865430 | Autism Spectrum Disorders | PASM |