| Entrez Gene ID |
2822 |
| Official Gene Symbol |
GPLD1 (GeneCards) |
| Full name |
glycosylphosphatidylinositol specific phospholipase D1 |
| Location |
6p22.3 |
| Other ids |
Vega : OTTHUMG00000016104
MIM : 602515
HGNC : HGNC:4459
Ensembl : ENSG00000112293
|
| Other names |
PLD,
GPIPLD,
PIGPLD,
GPIPLDM,
PIGPLD1
|
| Summary |
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008] |