| Entrez Gene ID | 2869 |
|---|---|
| Official Gene Symbol | GRK5 (GeneCards) |
| Full name | G protein-coupled receptor kinase 5 |
| Location | 10q26.11 |
| Other ids | Vega : OTTHUMG00000019149 MIM : 600870 HGNC : HGNC:4544 Ensembl : ENSG00000198873 |
| Other names | GPRK5 |
| Summary | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008] |
Found 4 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 14134 | 2869 | GRK5 | 10 | 121129295 | 121129295 | Asymptomatic | HiSeq X Ten |
| 14645 | 2869 | GRK5 | 10 | 121001467 | 121001467 | Asymptomatic | HiSeq X Ten |
| 14761 | 2869 | GRK5 | 10 | 120986953 | 120986953 | Cockayne syndrome | HiSeq X Ten |
| 29306 | 2869 | GRK5 | 10 | 121212266 | 121212266 | Autism Spectrum Disorders | HiSeq X Ten PASM |