| Entrez Gene ID | 2977 |
|---|---|
| Official Gene Symbol | GUCY1A2 (GeneCards) |
| Full name | guanylate cyclase 1 soluble subunit alpha 2 |
| Location | 11q22.3 |
| Other ids | Vega : OTTHUMG00000166296 MIM : 601244 HGNC : HGNC:4684 Ensembl : ENSG00000152402 |
| Other names | GC-SA2, GUC1A2 |
| Summary | Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
Found 10 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 15145 | 2977 | GUCY1A2 | 11 | 106906021 | 106906021 | Asymptomatic | HiSeq X Ten |
| 15178 | 2977 | GUCY1A2 | 11 | 106576775 | 106576775 | Asymptomatic | HiSeq X Ten |
| 15188 | 2977 | GUCY1A2 | 11 | 106941833 | 106941833 | Asymptomatic | HiSeq X Ten |
| 15329 | 2977 | GUCY1A2 | 11 | 106879745 | 106879745 | Asymptomatic | HiSeq X Ten |
| 15503 | 2977 | GUCY1A2 | 11 | 106597972 | 106597972 | Asymptomatic | HiSeq X Ten |
| 15678 | 2977 | GUCY1A2 | 11 | 107039201 | 107039201 | Asymptomatic | HiSeq X Ten |
| 15679 | 2977 | GUCY1A2 | 11 | 107053056 | 107053056 | Asymptomatic | HiSeq X Ten |
| 15996 | 2977 | GUCY1A2 | 11 | 106993524 | 106993524 | Xeroderma Pigmentosum | HiSeq X Ten |
| 27305 | 2977 | GUCY1A2 | 11 | 106728218 | 106728218 | Asymptomatic | HiSeq X Ten Single cell Sequencing Cell cloning |
| 29328 | 2977 | GUCY1A2 | 11 | 106681067 | 106681067 | Autism Spectrum Disorders | HiSeq X Ten Single cell Sequencing Cell cloning MiSeq |