NRG1 (Entrez ID: 3084)

Entrez Gene ID	3084
Official Gene Symbol	NRG1 (GeneCards)
Full name	neuregulin 1
Location	8p12
Other ids	Vega : OTTHUMG00000163918 MIM : 142445 HGNC : HGNC:7997 Ensembl : ENSG00000157168
Other names	GGF, HGL, HRG, NDF, ARIA, GGF2, HRG1, HRGA, SMDF, MST131, MSTP131, NRG1-IT2
Summary	The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]

Variants

Found 23 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
11601	3084	NRG1	8	32838293	32838293	Asymptomatic	HiSeq X Ten
11620	3084	NRG1	8	32247469	32247469	Asymptomatic	HiSeq X Ten
11714	3084	NRG1	8	32691851	32691851	Asymptomatic	HiSeq X Ten HiSeq 2000
11805	3084	NRG1	8	32008748	32008748	Asymptomatic	HiSeq X Ten HiSeq 2000
11891	3084	NRG1	8	31751395	31751395	Asymptomatic	HiSeq X Ten HiSeq 2000
11892	3084	NRG1	8	31751396	31751396	Asymptomatic	HiSeq X Ten HiSeq 2000
11981	3084	NRG1	8	32259216	32259216	Asymptomatic	HiSeq X Ten HiSeq 2000
12094	3084	NRG1	8	31703665	31703665		HiSeq X Ten HiSeq 2000
12174	3084	NRG1	8	32440318	32440318	Asymptomatic	HiSeq X Ten HiSeq 2000
12190	3084	NRG1	8	32331599	32331599	Asymptomatic	HiSeq X Ten HiSeq 2000
12398	3084	NRG1	8	32166806	32166806	Asymptomatic	HiSeq X Ten HiSeq 2000
12488	3084	NRG1	8	31690806	31690806	Asymptomatic	HiSeq X Ten HiSeq 2000
12562	3084	NRG1	8	33059494	33059494	Asymptomatic	HiSeq X Ten HiSeq 2000
12642	3084	NRG1	8	32343851	32343851	Cockayne syndrome	HiSeq X Ten HiSeq 2000
12695	3084	NRG1	8	32314579	32314579	Cockayne syndrome	HiSeq X Ten HiSeq 2000
12696	3084	NRG1	8	32494233	32494233	Cockayne syndrome	HiSeq X Ten HiSeq 2000
12729	3084	NRG1	8	31616368	31616368	Cockayne syndrome	HiSeq X Ten HiSeq 2000
26547	3084	NRG1	8	32931034	32931034	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26585	3084	NRG1	8	31633039	31633039	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26597	3084	NRG1	8	32801412	32801412	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26612	3084	NRG1	8	32868163	32868163	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26613	3084	NRG1	8	32868164	32868164	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26696	3084	NRG1	8	32640140	32640140	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning