APCS (Entrez ID: 325)

Entrez Gene ID 325
Official Gene Symbol APCS (GeneCards)
Full name amyloid P component, serum
Location 1q23.2
Other ids Vega : OTTHUMG00000022741
MIM : 104770
HGNC : HGNC:584
Ensembl : ENSG00000132703
Other names SAP, PTX2, HEL-S-92n
Summary The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]

Variants

Found 2 variants in this database.