| Entrez Gene ID |
329 |
| Official Gene Symbol |
BIRC2 (GeneCards) |
| Full name |
baculoviral IAP repeat containing 2 |
| Location |
11q22.2 |
| Other ids |
Vega : OTTHUMG00000167325
MIM : 601712
HGNC : HGNC:590
Ensembl : ENSG00000110330
|
| Other names |
API1,
MIHB,
HIAP2,
RNF48,
cIAP1,
Hiap-2,
c-IAP1
|
| Summary |
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |