HTR2A (Entrez ID: 3356)

Entrez Gene ID	3356
Official Gene Symbol	HTR2A (GeneCards)
Full name	5-hydroxytryptamine receptor 2A
Location	13q14.2
Other ids	Vega : OTTHUMG00000016881 MIM : 182135 HGNC : HGNC:5293 Ensembl : ENSG00000102468
Other names	HTR2, 5-HT2A
Summary	This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Variants

Found 12 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
17173	3356	HTR2A	13	48141915	48141915	Asymptomatic	HiSeq 2000
17198	3356	HTR2A	13	47995295	47995295	Asymptomatic	HiSeq 2000
17266	3356	HTR2A	13	47448675	47448675	Asymptomatic	HiSeq 2000 HiSeq X Ten
17280	3356	HTR2A	13	47438621	47438621	Asymptomatic	HiSeq 2000 HiSeq X Ten
17481	3356	HTR2A	13	48205548	48205548	Asymptomatic	HiSeq 2000 HiSeq X Ten
17482	3356	HTR2A	13	48222184	48222184	Asymptomatic	HiSeq 2000 HiSeq X Ten
17497	3356	HTR2A	13	47625237	47625237	Asymptomatic	HiSeq 2000 HiSeq X Ten
17724	3356	HTR2A	13	48204449	48204449	Asymptomatic	HiSeq 2000 HiSeq X Ten
17809	3356	HTR2A	13	47512721	47512721	Cockayne syndrome	HiSeq 2000 HiSeq X Ten
17874	3356	HTR2A	13	48118837	48118837	Cockayne syndrome	HiSeq 2000 HiSeq X Ten
17948	3356	HTR2A	13	48269798	48269798	Xeroderma Pigmentosum	HiSeq 2000 HiSeq X Ten
27709	3356	HTR2A	13	47705608	47705608	Asymptomatic	HiSeq 2000 HiSeq X Ten Single cell Sequencing Cell cloning