IGFBP3 (Entrez ID: 3486)

Entrez Gene ID	3486
Official Gene Symbol	IGFBP3 (GeneCards)
Full name	insulin like growth factor binding protein 3
Location	7p12.3
Other ids	Vega : OTTHUMG00000023769 MIM : 146732 HGNC : HGNC:5472 Ensembl : ENSG00000146674
Other names	IBP3, BP-53
Summary	This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Variants

Found 29 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
10357	3486	IGFBP3	7	46330873	46330873	Asymptomatic	HiSeq X Ten
10448	3486	IGFBP3	7	47285628	47285628	Asymptomatic	HiSeq X Ten HiSeq 2000
10485	3486	IGFBP3	7	47166024	47166024	Asymptomatic	HiSeq X Ten HiSeq 2000
10509	3486	IGFBP3	7	46654557	46654557	Asymptomatic	HiSeq X Ten HiSeq 2000
10551	3486	IGFBP3	7	47272111	47272111	Asymptomatic	HiSeq X Ten HiSeq 2000
10584	3486	IGFBP3	7	46337723	46337723	Asymptomatic	HiSeq X Ten HiSeq 2000
10585	3486	IGFBP3	7	46641346	46641346	Asymptomatic	HiSeq X Ten HiSeq 2000
10631	3486	IGFBP3	7	47112692	47112692	Asymptomatic	HiSeq X Ten HiSeq 2000
10813	3486	IGFBP3	7	46946025	46946025	Asymptomatic	HiSeq X Ten HiSeq 2000
10894	3486	IGFBP3	7	46167113	46167113	Asymptomatic	HiSeq X Ten HiSeq 2000
11052	3486	IGFBP3	7	47178661	47178661	Asymptomatic	HiSeq X Ten HiSeq 2000
11105	3486	IGFBP3	7	46018744	46018744	Asymptomatic	HiSeq X Ten HiSeq 2000
11168	3486	IGFBP3	7	46221647	46221647	Asymptomatic	HiSeq X Ten HiSeq 2000
11270	3486	IGFBP3	7	46921402	46921402	Asymptomatic	HiSeq X Ten HiSeq 2000
11305	3486	IGFBP3	7	46841541	46841541	Asymptomatic	HiSeq X Ten HiSeq 2000
11344	3486	IGFBP3	7	46493150	46493150	Cockayne syndrome	HiSeq X Ten HiSeq 2000
11463	3486	IGFBP3	7	46025351	46025351	Cockayne syndrome	HiSeq X Ten HiSeq 2000
11464	3486	IGFBP3	7	46506159	46506159	Cockayne syndrome	HiSeq X Ten HiSeq 2000
11544	3486	IGFBP3	7	47058702	47058702	Xeroderma Pigmentosum	HiSeq X Ten HiSeq 2000
23211	3486	IGFBP3	7	47022707	47022707	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26357	3486	IGFBP3	7	46102817	46102817	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26369	3486	IGFBP3	7	46406869	46406869	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26383	3486	IGFBP3	7	47068701	47068701	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26409	3486	IGFBP3	7	47001702	47001702	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26410	3486	IGFBP3	7	47039585	47039585	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26448	3486	IGFBP3	7	46013926	46013926	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26475	3486	IGFBP3	7	46235642	46235642	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
26504	3486	IGFBP3	7	46312834	46312834	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning
34414	3486	IGFBP3	7	45954799	45954799	Asymptomatic	HiSeq X Ten HiSeq 2000 Single cell Sequencing Cell cloning Whole Genome Sequencing Ion Torrent PGM Sequencing