| Entrez Gene ID | 3899 |
|---|---|
| Official Gene Symbol | AFF3 (GeneCards) |
| Full name | AF4/FMR2 family member 3 |
| Location | 2q11.2 |
| Other ids | Vega : OTTHUMG00000153011 MIM : 601464 HGNC : HGNC:6473 Ensembl : ENSG00000144218 |
| Other names | LAF4, MLLT2-like |
| Summary | This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008] |
Found 4 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 3760 | 3899 | AFF3 | 2 | 100590292 | 100590292 | Asymptomatic | HiSeq X Ten |
| 4189 | 3899 | AFF3 | 2 | 100566885 | 100566885 | Asymptomatic | HiSeq X Ten |
| 4281 | 3899 | AFF3 | 2 | 100483176 | 100483176 | Cockayne syndrome | HiSeq X Ten |
| 22667 | 3899 | AFF3 | 2 | 100452415 | 100452415 | Asymptomatic | HiSeq X Ten Single cell Sequencing Cell cloning |