| Entrez Gene ID | 4353 |
|---|---|
| Official Gene Symbol | MPO (GeneCards) |
| Full name | myeloperoxidase |
| Location | 17q22 |
| Other ids | Vega : OTTHUMG00000178922 MIM : 606989 HGNC : HGNC:7218 Ensembl : ENSG00000005381 |
| Other names | None |
| Summary | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] |
Found 1 variant in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 29676 | 4353 | MPO | 17 | 56356401 | 56356401 | Autism Spectrum Disorders | MiSeq |