NFKBIA (Entrez ID: 4792)

Entrez Gene ID 4792
Official Gene Symbol NFKBIA (GeneCards)
Full name NFKB inhibitor alpha
Location 14q13.2
Other ids Vega : OTTHUMG00000140220
MIM : 164008
HGNC : HGNC:7797
Ensembl : ENSG00000100906
Other names IKBA, MAD-3, NFKBI
Summary This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Variants

Found 4 variants in this database.