| Entrez Gene ID |
51057 |
| Official Gene Symbol |
WDPCP (GeneCards) |
| Full name |
WD repeat containing planar cell polarity effector |
| Location |
2p15 |
| Other ids |
Vega : OTTHUMG00000152566
MIM : 613580
HGNC : HGNC:28027
Ensembl : ENSG00000143951
|
| Other names |
FRTZ,
BBS15,
FRITZ,
CHDTHP,
C2orf86,
CPLANE5
|
| Summary |
This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |