| Entrez Gene ID |
51253 |
| Official Gene Symbol |
MRPL37 (GeneCards) |
| Full name |
mitochondrial ribosomal protein L37 |
| Location |
1p32.3 |
| Other ids |
Vega : OTTHUMG00000008118
MIM : 611843
HGNC : HGNC:14034
Ensembl : ENSG00000116221
|
| Other names |
L2mt,
L37mt,
MRPL2,
RPML2,
MRP-L2,
MRP-L37
|
| Summary |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008] |