PDE1C (Entrez ID: 5137)

Entrez Gene ID 5137
Official Gene Symbol PDE1C (GeneCards)
Full name phosphodiesterase 1C
Location 7p14.3
Other ids Vega : OTTHUMG00000023836
MIM : 602987
HGNC : HGNC:8776
Ensembl : ENSG00000154678
Other names Hcam3, hCam-3, cam-PDE1C
Summary This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]

Variants

Found 11 variants in this database.