| Entrez Gene ID |
5294 |
| Official Gene Symbol |
PIK3CG (GeneCards) |
| Full name |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| Location |
7q22.3 |
| Other ids |
Vega : OTTHUMG00000157641
MIM : 601232
HGNC : HGNC:8978
Ensembl : ENSG00000105851
|
| Other names |
PI3K,
PIK3,
PI3CG,
PI3Kgamma,
p110gamma,
p120-PI3K
|
| Summary |
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015] |