| Entrez Gene ID |
53919 |
| Official Gene Symbol |
SLCO1C1 (GeneCards) |
| Full name |
solute carrier organic anion transporter family member 1C1 |
| Location |
12p12.2 |
| Other ids |
Vega : OTTHUMG00000168966
MIM : 613389
HGNC : HGNC:13819
Ensembl : ENSG00000139155
|
| Other names |
OATP1,
OATPF,
OATP-F,
OATP14,
OATP1C1,
OATPRP5,
SLC21A14
|
| Summary |
This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] |