| Entrez Gene ID | 5496 |
|---|---|
| Official Gene Symbol | PPM1G (GeneCards) |
| Full name | protein phosphatase, Mg2+/Mn2+ dependent 1G |
| Location | 2p23.3 |
| Other ids | Vega : OTTHUMG00000097788 MIM : 605119 HGNC : HGNC:9278 Ensembl : ENSG00000115241 |
| Other names | PP2CG, PPP2CG, PP2CGAMMA |
| Summary | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010] |
Found 1 variant in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 29722 | 5496 | PPM1G | 2 | 27604615 | 27604615 | Autism Spectrum Disorders | NextSeq500 |