PDPR (Entrez ID: 55066)

Entrez Gene ID 55066
Official Gene Symbol PDPR (GeneCards)
Full name pyruvate dehydrogenase phosphatase regulatory subunit
Location 16q22.1
Other ids Vega : OTTHUMG00000176963
MIM : 617835
HGNC : HGNC:30264
Ensembl : ENSG00000090857
Other names PDP3
Summary Pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyzed by pyruvate dehydrogenase phosphatase (PDP). The dimeric PDP has a catalytic subunit and a regulatory subunit. This gene encodes the FAD-containing regulatory subunit of PDP. The encoded protein acts to decrease the sensitivity of the PDP catalytic subunit to magnesium ions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]

Variants

Found 4 variants in this database.