| Entrez Gene ID |
55118 |
| Official Gene Symbol |
CRTAC1 (GeneCards) |
| Full name |
cartilage acidic protein 1 |
| Location |
10q24.2 |
| Other ids |
Vega : OTTHUMG00000018871
MIM : 606276
HGNC : HGNC:14882
Ensembl : ENSG00000095713
|
| Other names |
ASPIC,
CEP68,
LOTUS,
ASPIC1,
CEP-68
|
| Summary |
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |