| Entrez Gene ID | 55959 |
|---|---|
| Official Gene Symbol | SULF2 (GeneCards) |
| Full name | sulfatase 2 |
| Location | 20q13.12 |
| Other ids | Vega : OTTHUMG00000032675 MIM : 610013 HGNC : HGNC:20392 Ensembl : ENSG00000196562 |
| Other names | HSULF-2 |
| Summary | Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] |
Found 6 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 21265 | 55959 | SULF2 | 20 | 46542247 | 46542247 | Asymptomatic | HiSeq X Ten |
| 21400 | 55959 | SULF2 | 20 | 46508814 | 46508814 | Asymptomatic | HiSeq X Ten |
| 21449 | 55959 | SULF2 | 20 | 46487294 | 46487294 | Asymptomatic | HiSeq X Ten |
| 21450 | 55959 | SULF2 | 20 | 46591877 | 46591877 | Asymptomatic | HiSeq X Ten |
| 21495 | 55959 | SULF2 | 20 | 46446800 | 46446800 | Cockayne syndrome | HiSeq X Ten |
| 24066 | 55959 | SULF2 | 20 | 46426979 | 46426979 | Asymptomatic | HiSeq X Ten Single cell Sequencing Cell cloning |