RELN (Entrez ID: 5649)

Entrez Gene ID 5649
Official Gene Symbol RELN (GeneCards)
Full name reelin
Location 7q22.1
Other ids Vega : OTTHUMG00000157247
MIM : 600514
HGNC : HGNC:9957
Ensembl : ENSG00000189056
Other names RL, ETL7, LIS2, PRO1598
Summary This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Variants

Found 10 variants in this database.