| Entrez Gene ID | 57142 |
|---|---|
| Official Gene Symbol | RTN4 (GeneCards) |
| Full name | reticulon 4 |
| Location | 2p16.1 |
| Other ids | Vega : OTTHUMG00000129337 MIM : 604475 HGNC : HGNC:14085 Ensembl : ENSG00000115310 |
| Other names | ASY, NSP, NOGO, RTN-X, NSP-CL, RTN4-A, RTN4-C, RTN4-B1, RTN4-B2, NI220/250, Nbla00271, Nbla10545 |
| Summary | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
Found 5 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 849 | 57142 | RTN4 | 2 | 55253870 | 55253870 | Human Skin Fibroblasts | HiSeq 2500 |
| 3305 | 57142 | RTN4 | 2 | 55341678 | 55341678 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
| 3795 | 57142 | RTN4 | 2 | 55270036 | 55270036 | Asymptomatic | HiSeq 2500 HiSeq X Ten |
| 4508 | 57142 | RTN4 | 2 | 55213921 | 55213921 | Xeroderma Pigmentosum | HiSeq 2500 HiSeq X Ten |
| 4570 | 57142 | RTN4 | 2 | 55353858 | 55353858 | Xeroderma Pigmentosum | HiSeq 2500 HiSeq X Ten |