| Entrez Gene ID | 57337 |
|---|---|
| Official Gene Symbol | SENP7 (GeneCards) |
| Full name | SUMO specific peptidase 7 |
| Location | 3q12.3 |
| Other ids | Vega : OTTHUMG00000149927 MIM : 612846 HGNC : HGNC:30402 Ensembl : ENSG00000138468 |
| Other names | None |
| Summary | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
Found 3 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 5539 | 57337 | SENP7 | 3 | 101073493 | 101073493 | Asymptomatic | HiSeq X Ten |
| 5791 | 57337 | SENP7 | 3 | 101162080 | 101162080 | Cockayne syndrome | HiSeq X Ten |
| 25123 | 57337 | SENP7 | 3 | 101128231 | 101128231 | Asymptomatic | HiSeq X Ten Single cell Sequencing Cell cloning |