| Entrez Gene ID |
5747 |
| Official Gene Symbol |
PTK2 (GeneCards) |
| Full name |
protein tyrosine kinase 2 |
| Location |
8q24.3 |
| Other ids |
Vega : OTTHUMG00000067438
MIM : 600758
HGNC : HGNC:9611
Ensembl : ENSG00000169398
|
| Other names |
FAK,
FADK,
FAK1,
FRNK,
PPP1R71,
p125FAK,
pp125FAK
|
| Summary |
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017] |