| Entrez Gene ID | 57472 |
|---|---|
| Official Gene Symbol | CNOT6 (GeneCards) |
| Full name | CCR4-NOT transcription complex subunit 6 |
| Location | 5q35.3 |
| Other ids | Vega : OTTHUMG00000130935 MIM : 608951 HGNC : HGNC:14099 Ensembl : ENSG00000113300 |
| Other names | CCR4, Ccr4a |
| Summary | This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014] |
Found 1 variant in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 8608 | 57472 | CNOT6 | 5 | 179958141 | 179958141 | Cockayne syndrome | HiSeq X Ten |