HACE1 (Entrez ID: 57531)

Entrez Gene ID 57531
Official Gene Symbol HACE1 (GeneCards)
Full name HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
Location 6q16.3
Other ids Vega : OTTHUMG00000015287
MIM : 610876
HGNC : HGNC:21033
Ensembl : ENSG00000085382
Other names SPPRS
Summary This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]

Variants

Found 2 variants in this database.