| Entrez Gene ID | 5924 |
|---|---|
| Official Gene Symbol | RASGRF2 (GeneCards) |
| Full name | Ras protein specific guanine nucleotide releasing factor 2 |
| Location | 5q14.1 |
| Other ids | Vega : OTTHUMG00000119015 MIM : 606614 HGNC : HGNC:9876 Ensembl : ENSG00000113319 |
| Other names | GRF2, RAS-GRF2 |
| Summary | RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011] |
Found 5 variants in this database.
| Variant ID | Entrez Gene ID | Gene | Chromsome | Start | End | Disease | Method |
|---|---|---|---|---|---|---|---|
| 7509 | 5924 | RASGRF2 | 5 | 80359920 | 80359920 | Asymptomatic | HiSeq X Ten |
| 7607 | 5924 | RASGRF2 | 5 | 80463592 | 80463592 | Asymptomatic | HiSeq X Ten |
| 7777 | 5924 | RASGRF2 | 5 | 80302505 | 80302505 | Asymptomatic | HiSeq X Ten |
| 8234 | 5924 | RASGRF2 | 5 | 80355529 | 80355529 | Asymptomatic | HiSeq X Ten |
| 8386 | 5924 | RASGRF2 | 5 | 80366792 | 80366792 | Asymptomatic | HiSeq X Ten |