RORA (Entrez ID: 6095)

Entrez Gene ID	6095
Official Gene Symbol	RORA (GeneCards)
Full name	RAR related orphan receptor A
Location	15q22.2
Other ids	Vega : OTTHUMG00000132769 MIM : 600825 HGNC : HGNC:10258 Ensembl : ENSG00000069667
Other names	ROR1, ROR2, ROR3, RZRA, NR1F1, RZR-ALPHA
Summary	The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]

Variants

Found 19 variants in this database.

Variant ID	Entrez Gene ID	Gene	Chromsome	Start	End	Disease	Method
1528	6095	RORA	15	60789727	60789727	Multiple Sclerosis	sequencing
18756	6095	RORA	15	61199596	61199596	Asymptomatic	sequencing HiSeq X Ten
18830	6095	RORA	15	61234377	61234377	Asymptomatic	sequencing HiSeq X Ten
18844	6095	RORA	15	61462144	61462144	Asymptomatic	sequencing HiSeq X Ten
18850	6095	RORA	15	61963327	61963327	Asymptomatic	sequencing HiSeq X Ten
18914	6095	RORA	15	61274856	61274856	Asymptomatic	sequencing HiSeq X Ten
18938	6095	RORA	15	61279639	61279639	Asymptomatic	sequencing HiSeq X Ten
18966	6095	RORA	15	61432101	61432101	Asymptomatic	sequencing HiSeq X Ten
18967	6095	RORA	15	61517128	61517128	Asymptomatic	sequencing HiSeq X Ten
19000	6095	RORA	15	62086698	62086698	Asymptomatic	sequencing HiSeq X Ten
19042	6095	RORA	15	61197177	61197177	Asymptomatic	sequencing HiSeq X Ten
19047	6095	RORA	15	61852784	61852784	Asymptomatic	sequencing HiSeq X Ten
19083	6095	RORA	15	61031179	61031179	Asymptomatic	sequencing HiSeq X Ten
19149	6095	RORA	15	62061224	62061224	Asymptomatic	sequencing HiSeq X Ten
19248	6095	RORA	15	61225031	61225031	Cockayne syndrome	sequencing HiSeq X Ten
19295	6095	RORA	15	61785346	61785346	Xeroderma Pigmentosum	sequencing HiSeq X Ten
28068	6095	RORA	15	61833805	61833805	Asymptomatic	sequencing HiSeq X Ten Single cell Sequencing Cell cloning
28087	6095	RORA	15	61823749	61823749	Asymptomatic	sequencing HiSeq X Ten Single cell Sequencing Cell cloning
28093	6095	RORA	15	61030746	61030746	Asymptomatic	sequencing HiSeq X Ten Single cell Sequencing Cell cloning