| Entrez Gene ID |
6614 |
| Official Gene Symbol |
SIGLEC1 (GeneCards) |
| Full name |
sialic acid binding Ig like lectin 1 |
| Location |
20p13 |
| Other ids |
Vega : OTTHUMG00000031757
MIM : 600751
HGNC : HGNC:11127
Ensembl : ENSG00000088827
|
| Other names |
SN,
CD169,
SIGLEC-1,
dJ1009E24.1
|
| Summary |
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008] |