| Entrez Gene ID |
774 |
| Official Gene Symbol |
CACNA1B (GeneCards) |
| Full name |
calcium voltage-gated channel subunit alpha1 B |
| Location |
9q34.3 |
| Other ids |
Vega : OTTHUMG00000021002
MIM : 601012
HGNC : HGNC:1389
Ensembl : ENSG00000148408
|
| Other names |
BIII,
CACNN,
DYT23,
Cav2.2,
CACNL1A5
|
| Summary |
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |